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DOCK5 and DOCK1 Regulate Caco-2 Intestinal Epithelial Cell Spreading and Migration on Collagen IV

We observed previously that combined small interfering RNAs (siRNAs) targeting CrkII and CrkL, known activators of guanine nucleotide exchange factor DOCK1, strongly inhibit Caco-2 intestinal epithelial cell spreading and migration on collagen IV. DOCK1 siRNA reduced its expression >95% in Caco-2...

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Detalhes bibliográficos
Main Authors: Sanders, Matthew A., Ampasala, Dinakar, Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610524/
https://ncbi.nlm.nih.gov/pubmed/19004829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808010200
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