DOCK5 and DOCK1 Regulate Caco-2 Intestinal Epithelial Cell Spreading and Migration on Collagen IV

We observed previously that combined small interfering RNAs (siRNAs) targeting CrkII and CrkL, known activators of guanine nucleotide exchange factor DOCK1, strongly inhibit Caco-2 intestinal epithelial cell spreading and migration on collagen IV. DOCK1 siRNA reduced its expression >95% in Caco-2...

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Bibliographische Detailangaben
Hauptverfasser: Sanders, Matthew A., Ampasala, Dinakar, Basson, Marc D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Molecular Basis of Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610524/
https://ncbi.nlm.nih.gov/pubmed/19004829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808010200
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