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Collagen IV regulates Caco-2 cell spreading and p130(Cas) phosphorylation by FAK-dependent and FAK-independent pathways

We previously observed that collagen IV regulates Caco-2 intestinal epithelial cell spreading and migration via Src-dependent p130(Cas) phosphorylation and stimulates focal adhesion kinase (FAK). However, the role of FAK and the related kinase, Pyk2, in Caco-2 spreading and migration is unclear. FAK...

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Detalles Bibliográficos
Main Authors: Sanders, Matthew A., Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614921/
https://ncbi.nlm.nih.gov/pubmed/18095869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2008.008
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