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Propofol inhibits pressure-stimulated macrophage phagocytosis via the GABA(A) receptor and dysregulation of p130cas phosphorylation

Surgical stress and anesthesia result in systemic immunosuppression. Propofol, a commonly used anesthetic agent, alters immune cell functions. Previously, we demonstrated that extracellular pressure increases macrophage phagocytosis. We hypothesized that propofol might influence pressure-induced mac...

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Detalhes bibliográficos
Main Authors: Shiratsuchi, Hiroe, Kouatli, Yasser, Yu, Guang Xiang, Marsh, Harold M., Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692417/
https://ncbi.nlm.nih.gov/pubmed/19357231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00345.2008
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