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Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41

The membrane proximal region (MPR) of HIV-1 gp41 is a desirable target for development of a vaccine that elicits neutralizing antibodies since the patient-derived monoclonal antibodies, 2F5 and 4E10, bind to the MPR and neutralize primary HIV isolates. The 2F5 and 4E10 antibodies cross-react with li...

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Hlavní autoři: Watson, Douglas S., Szoka, Francis C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730955/
https://ncbi.nlm.nih.gov/pubmed/19520200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.05.059
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