Structural Characterization of HIV gp41 with the Membrane-proximal External Region

Human immunodeficiency virus, type 1 (HIV-1) envelope glycoprotein (gp120/gp41) plays a critical role in virus infection and pathogenesis. Three of the six monoclonal antibodies considered to have broadly neutralizing activities (2F5, 4E10, and Z13e1) bind to the membrane-proximal external region (M...

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Hlavní autoři: Shi, Wuxian, Bohon, Jen, Han, Dong P., Habte, Habtom, Qin, Yali, Cho, Michael W., Chance, Mark R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911339/
https://ncbi.nlm.nih.gov/pubmed/20525690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111351
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