Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions

The HIV-1 envelope glycoprotein (Env) composed of the receptor binding domain gp120 and the fusion protein subunit gp41 catalyzes virus entry and is a major target for therapeutic intervention and for neutralizing antibodies. Env interactions with cellular receptors trigger refolding of gp41, which...

Full description

Saved in:
Bibliographic Details
Main Authors: Buzon, Victor, Natrajan, Ganesh, Schibli, David, Campelo, Felix, Kozlov, Michael M., Weissenhorn, Winfried
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865522/
https://ncbi.nlm.nih.gov/pubmed/20463810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000880
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items