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Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region
The monoclonal antibody 13H11 shares part of its epitope in the HIV-1 gp41 membrane-proximal external region (MPER) with the rare, broadly neutralizing human antibody 2F5. Although 13H11 partially cross-blocked 2F5 binding, 13H11 is non-neutralizing and does not block 2F5 neutralization. We show tha...
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6081738/ https://ncbi.nlm.nih.gov/pubmed/21076400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1944 |
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