Initial Stages of V(D)J Recombination: the Organization of RAG1/2 and RSS DNA in the Post-cleavage Complex

To obtain structural information on the early stages of V(D)J recombination, we isolated a complex of the core RAG1 and RAG2 proteins with DNA containing a pair of cleaved recombination signal sequences (RSS). Stoichiometric and molecular mass analysis established that this signal end complex (SEC)...

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Main Authors: Grundy, Gabrielle J., Ramón-Maiques, Santiago, Dimitriadis, Emilios K., Kotova, Svetlana, Biertümpfel, Christian, Heymann, J. Bernard, Steven, Alasdair C., Gellert, Martin, Yang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730168/
https://ncbi.nlm.nih.gov/pubmed/19647518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.022
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