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Structural gymnastics of RAG-mediated DNA cleavage in V(D)J recombination
A hallmark of vertebrate immunity is the diverse repertoire of antigen-receptor genes that results from combinatorial splicing of gene coding segments by V(D)J recombination. The (RAG1-RAG2)(2) endonuclease complex (RAG) specifically recognizes and cleaves a pair of recombination signal sequences (R...
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| Yayımlandı: | Curr Opin Struct Biol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6457668/ https://ncbi.nlm.nih.gov/pubmed/30476719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2018.11.001 |
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