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Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death

Purkinje cells are a class of specialized neurons in the cerebellum, and are among the most metabolically active of all neurons, as they receive immense synaptic stimulation, and provide the only efferent output from the cerebellum. Degeneration of Purkinje cells is a common feature of inherited ata...

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Bibliografske podrobnosti
Main Authors: Chakrabarti, Lisa, Eng, Jeremiah, Ivanov, Nishi, Garden, Gwenn A, La Spada, Albert R
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729476/
https://ncbi.nlm.nih.gov/pubmed/19640278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-24
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