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Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death

Purkinje cells are a class of specialized neurons in the cerebellum, and are among the most metabolically active of all neurons, as they receive immense synaptic stimulation, and provide the only efferent output from the cerebellum. Degeneration of Purkinje cells is a common feature of inherited ata...

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Autors principals: Chakrabarti, Lisa, Eng, Jeremiah, Ivanov, Nishi, Garden, Gwenn A, La Spada, Albert R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729476/
https://ncbi.nlm.nih.gov/pubmed/19640278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-24
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