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CK2 negatively regulates Gα(s) signaling
We present evidence, using biochemical and cellular approaches, that the kinase, CK2, negatively controls signaling via Gα(s) (or Gα(olf)) coupled to dopamine D1 and adenosine A2A receptors. Pharmacological inhibition of CK2 or CK2 knockdown by RNAi lead to elevated cAMP levels in dopamine D1 recept...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729026/ https://ncbi.nlm.nih.gov/pubmed/19666609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906857106 |
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