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Selective knockout of the CK2 kinase in D1 medium spiny neurons controls dopaminergic function

BACKGROUND: Dopamine, crucial for the regulation of motor function and reward, acts through receptors mainly expressed in striatum as well as cortex. Dysregulation of dopaminergic signaling is associated with various neuropsychiatric disorders. Consequently, dopamine-regulating drugs are effectively...

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Autors principals: Rebholz, Heike, Zhou, Mingming, Nairn, Angus C., Greengard, Paul, Flajolet, Marc
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878430/
https://ncbi.nlm.nih.gov/pubmed/23290496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.11.013
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