Real-time in vivo imaging of p16(Ink4a) reveals cross talk with p53

Expression of the p16(Ink4a) tumor suppressor gene, a sensor of oncogenic stress, is up-regulated by a variety of potentially oncogenic stimuli in cultured primary cells. However, because p16(Ink4a) expression is also induced by tissue culture stress, physiological mechanisms regulating p16(Ink4a) e...

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Main Authors: Yamakoshi, Kimi, Takahashi, Akiko, Hirota, Fumiko, Nakayama, Rika, Ishimaru, Naozumi, Kubo, Yoshiaki, Mann, David J., Ohmura, Masako, Hirao, Atsushi, Saya, Hideyuki, Arase, Seiji, Hayashi, Yoshio, Nakao, Kazuki, Matsumoto, Mitsuru, Ohtani, Naoko, Hara, Eiji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2009
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728398/
https://ncbi.nlm.nih.gov/pubmed/19667129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200904105
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