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Rescue of PreTCR but not Mature TCR Signaling in Mice Expressing Membrane-Targeted SLP-76
SLP-76 (SH2 domain-containing leukocyte phosphoprotein of 76 kDa) organizes signaling from immunoreceptors, including the platelet collagen receptor, the preTCR and TCR, and is required for T cell development. Here we examine a mouse in which wildtype SLP-76 is replaced with a mutant constitutively...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2727718/ https://ncbi.nlm.nih.gov/pubmed/19380761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802176 |
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