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Tandem Action of the O(2)- and FADH(2)-Dependent Halogenases KtzQ and KtzR Produce 6,7-Dichlorotryptophan for Kutzneride Assembly

[Image: see text] Kutznerides are actinomycete-derived antifungal nonribosomal hexadepsipeptides which are assembled from five unsual nonproteinogenic amino acids and one hydroxy acid. Conserved in all structurally characterized kutznerides is a dichlorinated tricyclic hexahydropyrroloindole postula...

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Detaylı Bibliyografya
Asıl Yazarlar: Heemstra, John R., Walsh, Christopher T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726796/
https://ncbi.nlm.nih.gov/pubmed/18828589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806467a
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