Biosynthetic Chlorination of the Piperazate Residue in Kutzneride Biosynthesis by KthP

[Image: see text] Kutznerides 2 and 8 of the cyclic hexadepsipeptide family of antifungal natural products from the soil actinomycete Kutzneria sp. 744 contain two sets of chlorinated residues, a 6,7-dichlorohexahydropyrroloindole moiety derived from dichlorotryptophan and a 5-chloropiperazate moiet...

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Main Authors: Jiang, Wei, Heemstra, John R., Forseth, Ry R., Neumann, Christopher S., Manaviazar, Soraya, Schroeder, Frank C., Hale, Karl J., Walsh, Christopher T.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2011
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129693/
https://ncbi.nlm.nih.gov/pubmed/21648411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200656k
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