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Stereospecific Synthesis of threo- and erythro-β-Hydroxyglutamic Acid During Kutzneride Biosynthesis

The antifungal and antimicrobial kutznerides, hexadepsipeptides comprised of one α-hydroxy acid and five non-proteinogenic amino acids, are remarkable examples of the structural diversity found in nonribosomally-produced natural products. They contain D-3-hydroxyglutamic acid, which is found in the...

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Autores principales: Strieker, Matthias, Nolan, Elizabeth M., Walsh, Christopher T., Marahiel, Mohamed A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745491/
https://ncbi.nlm.nih.gov/pubmed/19722489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9054417
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