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Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis
The non-heme iron oxygenase VioC from Streptomyces vinaceus catalyzes Fe(II)- and α-ketoglutarate-dependent Cβ-hydroxylation of L-arginine during the biosynthesis of the tuberactinomycin antibiotic viomycin. Crystal structures of VioC were determined in complexes with the cofactor Fe(II), the substr...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771579/ https://ncbi.nlm.nih.gov/pubmed/19490124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.07085.x |
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