The Positive Allosteric Modulator Morantel Binds at Noncanonical Subunit Interfaces of Neuronal Nicotinic Acetylcholine Receptors

We are interested in the positive allosteric modulation of neuronal nicotinic acetylcholine (ACh) receptors and have recently shown that the anthelmintic compound morantel potentiates by enhancing channel gating of the α3β2 subtype. Based on the demonstration that morantel-elicited currents were inh...

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Detaylı Bibliyografya
Asıl Yazarlar: Seo, Seungmae, Henry, Jonathan T., Lewis, Amanda H., Wang, Nan, Levandoski, Mark M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2009
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726771/
https://ncbi.nlm.nih.gov/pubmed/19587280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1859-09.2009
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