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Specificity tuning of antibody fragments to neutralize two human chemokines with a single agent

Chemokines are important mediators of the immune response that are responsible for the trafficking of immune cells between lymphoid organs and migration towards sites of inflammation. Using phage display selection and a functional screening approach, we have isolated a panel of single-chain fragment...

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Bibliografiske detaljer
Main Authors: Fagète, Séverine, Ravn, Ulla, Gueneau, Franck, Magistrelli, Giovanni, Kosco-Vilbois, Marie H, Fischer, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726596/
https://ncbi.nlm.nih.gov/pubmed/20069756
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