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Soluble Fibrillar Oligomer Levels are Elevated in Alzheimer's Disease Brain and Correlate with Cognitive Dysfunction
Recent evidence has suggested a role for soluble oligomeric Aβ species in the pathology of Alzheime’s disease (AD). Fibrillar plaque deposits are present in non-demented individuals and levels of soluble Aβ correlate better with cognitive dysfunction in AD and transgenic mouse models. We have previo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725199/ https://ncbi.nlm.nih.gov/pubmed/19523517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.05.024 |
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