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Amyloid-β Annular Protofibrils Evade Fibrillar Fate in Alzheimer Disease Brain
Annular protofibrils (APFs) represent a new and distinct class of amyloid structures formed by disease-associated proteins. In vitro, these pore-like structures have been implicated in membrane permeabilization and ion homeostasis via pore formation. Still, evidence for their formation and relevance...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121356/ https://ncbi.nlm.nih.gov/pubmed/21507938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236257 |
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