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BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells
BCL6 is a transcriptional repressor protein that is expressed in a developmentally regulated fashion during B-cell maturation. Specifically, BCL6 is required for formation of germinal centers in response to T-cell dependent antigen activation. Germinal center B-cells feature the ability to tolerate...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723786/ https://ncbi.nlm.nih.gov/pubmed/18346918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2008.02.003 |
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