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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
Mammalian telomeres are associated with shelterin, the telomere specific protein complex that solves the end-protection problem. The telomeric shelterin binding sites, TTAGGG repeats, are maintained by telomerase, which solves the end-replication problem. We report that the TTAGGG repeat arrays of h...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2723738/ https://ncbi.nlm.nih.gov/pubmed/19596237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.021 |
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