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A TRF1-controlled common fragile site containing interstitial telomeric sequences
Mouse telomeres have been suggested to resemble common fragile sites (CFS), showing disrupted TTAGGG fluorescent in situ hybridization signals after aphidicolin treatment. This “fragile” telomere phenotype is induced by deletion of TRF1, a shelterin protein that binds telomeric DNA and promotes effi...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3590843/ https://ncbi.nlm.nih.gov/pubmed/22790221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-012-0377-6 |
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