TRF1 binds a bipartite telomeric site with extreme spatial flexibility.

TRF1 is a key player in telomere length regulation. Because length control was proposed to depend on the architecture of telomeres, we studied how TRF1 binds telomeric TTAGGG repeat DNA and alters its conformation. Although the single Myb-type helix-turn-helix motif of a TRF1 monomer can interact wi...

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Detalles Bibliográficos
Main Authors: Bianchi, A, Stansel, R M, Fairall, L, Griffith, J D, Rhodes, D, de Lange, T
Formato: Artigo
Idioma:Inglês
Publicado: 1999
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171640/
https://ncbi.nlm.nih.gov/pubmed/10523316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5735
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