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T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang
Mammalian telomeres contain a duplex TTAGGG-repeat tract terminating in a 3′ single-stranded overhang. TRF2 protein has been implicated in remodeling telomeres into duplex lariats, termed t-loops, in vitro and t-loops have been isolated from cells in vivo. To examine the features of the telomeric DN...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2001
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125642/ https://ncbi.nlm.nih.gov/pubmed/11574485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.19.5532 |
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