T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang
Mammalian telomeres contain a duplex TTAGGG-repeat tract terminating in a 3′ single-stranded overhang. TRF2 protein has been implicated in remodeling telomeres into duplex lariats, termed t-loops, in vitro and t-loops have been isolated from cells in vivo. To examine the features of the telomeric DN...
שמור ב:
| הוצא לאור ב: | EMBO J |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2001
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11574485/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.19.5532 |
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