T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang

Mammalian telomeres contain a duplex TTAGGG-repeat tract terminating in a 3′ single-stranded overhang. TRF2 protein has been implicated in remodeling telomeres into duplex lariats, termed t-loops, in vitro and t-loops have been isolated from cells in vivo. To examine the features of the telomeric DN...

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Detalles Bibliográficos

Publicado en:	EMBO J
Principais autores:	Stansel, Rachel M., de Lange, Titia, Griffith, Jack D.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2001
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11574485/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.19.5532
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