Laddar...
Different telomere damage signaling pathways in human and mouse cells
Programmed telomere shortening in human somatic cells is thought to act as a tumor suppressor pathway, limiting the replicative potential of developing tumor cells. Critically short human telomeres induce senescence either by activating p53 or by inducing the p16/RB pathway, and suppression of both...
Sparad:
| Huvudupphovsmän: | , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2002
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126171/ https://ncbi.nlm.nih.gov/pubmed/12169636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf433 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|