T-loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang

Mammalian telomeres contain a duplex TTAGGG-repeat tract terminating in a 3′ single-stranded overhang. TRF2 protein has been implicated in remodeling telomeres into duplex lariats, termed t-loops, in vitro and t-loops have been isolated from cells in vivo. To examine the features of the telomeric DN...

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Argitaratua izan da:	EMBO J
Egile Nagusiak:	Stansel, Rachel M., de Lange, Titia, Griffith, Jack D.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Publishing Group 2001
Gaiak:	Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11574485/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.19.5532
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