Anti-VEGF single-chain antibody GLAF-1 encoded by oncolytic vaccinia virus significantly enhances antitumor therapy

We previously reported that the replication-competent vaccinia virus (VACV) GLV-1h68 shows remarkable oncolytic activity and efficacy in different animal models as a single treatment modality and also in combination with chemotherapy [Yu YA, et al. (2009) Mol Cancer Ther 8:141–151]. Here, we report...

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Autors principals: Frentzen, Alexa, Yu, Yong A., Chen, Nanhai, Zhang, Qian, Weibel, Stephanie, Raab, Viktoria, Szalay, Aladar A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722284/
https://ncbi.nlm.nih.gov/pubmed/19617539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900660106
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