Preclinical Testing Oncolytic Vaccinia Virus Strain GLV-5b451 Expressing an Anti-VEGF Single-Chain Antibody for Canine Cancer Therapy

Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a novel approach for canine cancer therapy. Here we describe, for the first time, the characterization and the use of VACV strain GLV-5b451 expressing the anti-vascular endothelial growth factor (VEGF) single-chain antibody (scAb...

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Udgivet i:Viruses
Main Authors: Adelfinger, Marion, Bessler, Simon, Frentzen, Alexa, Cecil, Alexander, Langbein-Laugwitz, Johanna, Gentschev, Ivaylo, Szalay, Aladar A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517140/
https://ncbi.nlm.nih.gov/pubmed/26205404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7072811
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