Combination treatment with oncolytic Vaccinia virus and cyclophosphamide results in synergistic antitumor effects in human lung adenocarcinoma bearing mice

BACKGROUND: The capacity of the recombinant Vaccinia virus GLV-1h68 as a single agent to efficiently treat different human or canine cancers has been shown in several preclinical studies. Currently, its human safety and efficacy are investigated in phase I/II clinical trials. In this study we set ou...

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Bibliographic Details
Main Authors: Hofmann, Elisabeth, Weibel, Stephanie, Szalay, Aladar A
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4105246/
https://ncbi.nlm.nih.gov/pubmed/25030093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-197
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