Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen

Variable lymphocyte receptors (VLRs) are leucine-rich repeat (LRR) proteins that mediate adaptive immunity in jawless vertebrates. VLRs are fundamentally different from the antibodies of jawed vertebrates, which consist of immunoglobulin (Ig) domains. We determined the structure of an anti-hen egg w...

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Bibliografiske detaljer
Main Authors: Velikovsky, C Alejandro, Deng, Lu, Tasumi, Satoshi, Iyer, Lakshminarayan M, Kerzic, Melissa C, Aravind, L, Pancer, Zeev, Mariuzza, Roy A
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722044/
https://ncbi.nlm.nih.gov/pubmed/19543291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1619
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