A structural basis for antigen recognition by the T cell-like lymphocytes of sea lamprey

Adaptive immunity in jawless vertebrates is mediated by leucine-rich repeat proteins called “variable lymphocyte receptors” (VLRs). Two types of VLR (A and B) are expressed by mutually exclusive lymphocyte populations in lamprey. VLRB lymphocytes resemble the B cells of jawed vertebrates; VLRA lymph...

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Autori principali: Deng, Lu, Velikovsky, C. Alejandro, Xu, Gang, Iyer, Lakshminarayan M., Tasumi, Satoshi, Kerzic, Melissa C., Flajnik, Martin F., Aravind, L., Pancer, Zeev, Mariuzza, Roy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922149/
https://ncbi.nlm.nih.gov/pubmed/20616002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005475107
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