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Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen

Variable lymphocyte receptors (VLRs) are leucine-rich repeat (LRR) proteins that mediate adaptive immunity in jawless vertebrates. VLRs are fundamentally different from the antibodies of jawed vertebrates, which consist of immunoglobulin (Ig) domains. We determined the structure of an anti-hen egg w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Velikovsky, C Alejandro, Deng, Lu, Tasumi, Satoshi, Iyer, Lakshminarayan M, Kerzic, Melissa C, Aravind, L, Pancer, Zeev, Mariuzza, Roy A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722044/
https://ncbi.nlm.nih.gov/pubmed/19543291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1619
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