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Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen

Variable lymphocyte receptors (VLRs) are leucine-rich repeat (LRR) proteins that mediate adaptive immunity in jawless vertebrates. VLRs are fundamentally different from the antibodies of jawed vertebrates, which consist of immunoglobulin (Ig) domains. We determined the structure of an anti-hen egg w...

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Detalhes bibliográficos
Main Authors: Velikovsky, C Alejandro, Deng, Lu, Tasumi, Satoshi, Iyer, Lakshminarayan M, Kerzic, Melissa C, Aravind, L, Pancer, Zeev, Mariuzza, Roy A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722044/
https://ncbi.nlm.nih.gov/pubmed/19543291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1619
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