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Multiple functions of MRN in end-joining pathways during isotype class switching
The Mre11/Rad50/NBS1 (MRN) complex plays many roles in response to DNA double strand breaks (DSBs), but its functions in repair by non homologous end joining (NHEJ) pathways are poorly understood. We have investigated requirements for MRN in Class Switch Recombination (CSR), a programmed DNA rearran...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2721910/ https://ncbi.nlm.nih.gov/pubmed/19633670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1639 |
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