Structure-based design of anticancer prodrug PABA/NO

Glutathione S-transferase (GST) is a superfamily of detoxification enzymes, represented by GSTα, GSTμ, GSTπ, etc. GSTα is the predominant isoform of GST in human liver, playing important roles for our well being. GSTπ is overexpressed in many forms of cancer, thus presenting an opportunity for selec...

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Detalhes bibliográficos
Main Authors: Ji, Xinhua, Pal, Ajai, Kalathur, Ravi, Hu, Xun, Gu, Yijun, Saavedra, Joseph E, Buzard, Gregory S, Srinivasan, Aloka, Keefer, Larry K, Singh, Shivendra V
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721280/
https://ncbi.nlm.nih.gov/pubmed/19662104
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