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Recent Trends in Targeted Anticancer Prodrug and Conjugate Design

Anticancer drugs are often nonselective antiproliferative agents (cytotoxins) that preferentially kill dividing cells by attacking their DNA at some level. The lack of selectivity results in significant toxicity to noncancerous proliferating cells. These toxicities along with drug resistance exhibit...

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Main Authors: Singh, Yashveer, Palombo, Matthew, Sinko, Patrick J.
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802226/
https://ncbi.nlm.nih.gov/pubmed/18691040
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