Structure-based design of anticancer prodrug PABA/NO

Glutathione S-transferase (GST) is a superfamily of detoxification enzymes, represented by GSTα, GSTμ, GSTπ, etc. GSTα is the predominant isoform of GST in human liver, playing important roles for our well being. GSTπ is overexpressed in many forms of cancer, thus presenting an opportunity for selec...

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Bibliografiske detaljer
Main Authors: Ji, Xinhua, Pal, Ajai, Kalathur, Ravi, Hu, Xun, Gu, Yijun, Saavedra, Joseph E, Buzard, Gregory S, Srinivasan, Aloka, Keefer, Larry K, Singh, Shivendra V
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2009
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721280/
https://ncbi.nlm.nih.gov/pubmed/19662104
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