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A Humanized Radioiodinated Minibody as an Imaging Agent for the Detection of Prostate Stem Cell Antigen (PSCA)-Expressing Tumors by microPET
PURPOSE: Prostate Stem Cell Antigen (PSCA) is a cell surface glycoprotein that is overexpressed in prostate cancer including hormone refractory disease. Previous preclinical studies showed the intact anti-PSCA antibodies, 1G8 and hu1G8, localized specifically to PSCA-expressing xenografts. Optimal m...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720761/ https://ncbi.nlm.nih.gov/pubmed/19010866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5093 |
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