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A Humanized Radioiodinated Minibody as an Imaging Agent for the Detection of Prostate Stem Cell Antigen (PSCA)-Expressing Tumors by microPET

PURPOSE: Prostate Stem Cell Antigen (PSCA) is a cell surface glycoprotein that is overexpressed in prostate cancer including hormone refractory disease. Previous preclinical studies showed the intact anti-PSCA antibodies, 1G8 and hu1G8, localized specifically to PSCA-expressing xenografts. Optimal m...

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Detalhes bibliográficos
Main Authors: Leyton, Jeffrey V., Olafsen, Tove, Lepin, Eric J., Hahm, Scott, Bauer, Karl B., Reiter, Robert E., Wu, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720761/
https://ncbi.nlm.nih.gov/pubmed/19010866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5093
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