An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors

PURPOSE: Prostate stem cell antigen (PSCA), a cell surface glycoprotein expressed in normal human prostate and bladder, is over-expressed in the majority of localized prostate cancer and most bone metastases. We have previously shown that the hu1G8 minibody, a humanized anti-PSCA antibody fragment (...

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Autori principali: Lepin, Eric J., Leyton, Jeffrey V., Zhou, Yu, Olafsen, Tove, Salazar, Felix B., McCabe, Katelyn E., Hahm, Scott, Marks, James D., Reiter, Robert E., Wu, Anna M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903645/
https://ncbi.nlm.nih.gov/pubmed/20354850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1433-1
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