Quantitative ImmunoPET of Prostate Cancer Xenografts with (89)Zr- and (124)I-Labeled Anti-PSCA A11 Minibody

Prostate stem cell antigen (PSCA) is expressed on the cell surface in 83%–100% of local prostate cancers and 87%–100% of prostate cancer bone metastases. In this study, we sought to develop immunoPET agents using (124)I- and (89)Zr-labeled anti-PSCA A11 minibodies (scFv-C(H)3 dimer, 80 kDa) and eval...

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Bibliografische gegevens
Hoofdauteurs: Knowles, Scott M., Zettlitz, Kirstin A., Tavaré, Richard, Rochefort, Matthew M., Salazar, Felix B., Stout, David B., Yazaki, Paul J., Reiter, Robert E., Wu, Anna M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052832/
https://ncbi.nlm.nih.gov/pubmed/24504052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.120873
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