NAD(+)-Dependent 15-Hydroxyprostaglandin Dehydrogenase Regulates Levels of Bioactive Lipids in Non–Small Cell Lung Cancer

Elevated levels of procarcinogenic prostaglandins (PG) are foundin a variety of human malignancies including non–small cell lung cancer (NSCLC). Overexpression of cyclooxygenase-2 and microsomal prostaglandin synthase 1 occurs in tumors and contributes to increased PG synthesis. NAD(+)-dependent 15-...

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Autores principales: Hughes, Duncan, Otani, Taisuke, Yang, Peiying, Newman, Robert A., Yantiss, Rhonda K., Altorki, Nasser K., Port, Jeff L., Yan, Min, Markowitz, Sanford D., Mazumdar, Madhu, Tai, Hsin-Hsiung, Subbaramaiah, Kotha, Dannenberg, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720569/
https://ncbi.nlm.nih.gov/pubmed/19138967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0055
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