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Identification of cross-linked peptides from large sequence databases

We describe a method to identify cross-linked peptides from complex samples and large protein sequence databases. The advance was achieved by combining isotopically tagged cross-linkers, chromatographic enrichment, targeted proteomics, and a novel search engine called xQuest. This software reduces t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rinner, Oliver, Seebacher, Jan, Walzthoeni, Thomas, Mueller, Lukas, Beck, Martin, Schmidt, Alexander, Mueller, Markus, Aebersold, Ruedi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719781/
https://ncbi.nlm.nih.gov/pubmed/18327264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1192
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