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An Integrated, Directed Mass Spectrometric Approach for In-depth Characterization of Complex Peptide Mixtures
LC-MS/MS has emerged as the method of choice for the identification and quantification of protein sample mixtures. For very complex samples such as complete proteomes, the most commonly used LC-MS/MS method, data-dependent acquisition (DDA) precursor selection, is of limited utility. The limited sca...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577211/ https://ncbi.nlm.nih.gov/pubmed/18511481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700498-MCP200 |
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